29 May 2012

Modest alcohol intake may benefit patients with common liver disease


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Wine

London, May 16 : Modest alcohol consumption has been found to be associated with less inflammation in patients with NAFLD (non-alcoholic fatty liver disease), the most common type of liver disease in the developed world.

NAFLD is often associated with obesity and other parameters of the so-called "metabolic syndrome," which is a major risk factor for the development of cardiovascular disease.

In a well-done study among subjects with NAFLD, the investigators have demonstrated that modest alcohol consumption (an average of up to 20 grams of alcohol per day and no binge drinking) is associated with less evidence of inflammation of the liver (steatohepatitis), a condition known to markedly increase the risk of progression of liver disease to cirrhosis.

Given that NAFLD and other conditions associated with the metabolic syndrome are so common, and are major risk factors for developing cardiovascular disease, the results of the present study are important.

They show that modest drinking is associated with decreased, not increased, inflammation of the liver.

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Further, even among subjects with NAFLD, cardiovascular disease is a much more common cause of death than liver disease.

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Long term use of Alcohol effect
The researchers suggested that intervention studies should be done to support their findings; if confirmed, subjects with NAFLD should not be advised to avoid all alcohol, which is the current advice usually given to such patients.

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